Interplay Between Diet, Gut Microbiota, Epigenetic Events, and Colorectal Cancer

Diet modulates gut microbiota, which in turn produces metabolites like butyrate and secondary bile acids that influence host epigenetics. These epigenetic modifications can silence tumor suppressor genes or activate oncogenes, contributing to colorectal cancer risk. This session highlights how dietary fiber, fat, and polyphenols shape microbial outputs and epigenomic regulation, with implications for dietary prevention and personalized nutrition in cancer.

 

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