The Microbiota in Early Life Shapes the Immune System
From birth, microbial exposure shapes immune cell development, especially in the gut-associated lymphoid tissue (GALT). The microbiota educates the immune system to distinguish between harmful and harmless stimuli, promoting tolerance and balanced responses. Early disruptions—due to C-section birth, formula feeding, or antibiotics—can increase risks for allergies, asthma, IBD, and autoimmune disorders. This session focuses on the critical window of microbial colonization and its long-lasting impact on immune regulation, discussing therapeutic strategies like probiotics and maternal microbiota transfer to restore optimal microbial programming in early life.
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