Souad Benaouf
faculty of Medecine of Oran Ahmed Benbella
Title: Modifications of oral microbiome during celiac disease and their oral manifestations
Biography
Biography: Souad Benaouf
Abstract
Introduction :The obtainment of oral microbiome starts as of the birth and evolves with time (during one’s life).During a symptomatic celiac disease an intestinal dysbiosis of a microbiome is noticed to be accompanied by a oral dysbiosis caused by a oral manifestations. Methods and Materials : This study was carried out at Oral Pathology and Orale Surgery at the Hospital of Oran Algeria from June 2014 to December 2018.The level of significance for statistical tests was set at 5%. The results are given with a confidence interval estimated at 95%. Results: On a sample of 108 celiac patients, The sex ratio is 1,04.The existence of black stains on the surface of the teeth is presented in a preponderant manner in the group of celiac patients with an effective of 43 patients being 39,8% of the cases contrary to 22 subject in the control group being 18,6% of the cases. The Chi-square test finds a statistically significant difference with a P = 0,002. Discussion :During a symptomatic celiac illness a dysbiosis of an intestinal microbiome is observed to have a predominant bacteria pro inflammatory and a bacteria gram negative. A small concentration of beneficial bacteria such as Lactobacillus and Bifidobacterium is however noticed. In the oral flora, some dysbiosis were observed especially the appearance of chromogenic bacteria usually absent of the normal oral microbiome (normobiose) also Actinomyces and A.Actinomycetemcomitans are responsible of the appearance of the black stains on the dental surface. Porphyromonas gingivalis and Prevotella melaninogenica were not proven to be helpful in the appearance of these stains Conclusion : The changes in the oral and intestinal microbiome directly on the innate immunity is adaptive because of pathophysiological links that unites